Moving into a care home is a significant and often life changing transition. Everyday objects can make this easier. Whilst it is widely believed that care homes encourage new residents to bring personal possessions with …
Research projects
Combining Memantine and Cholinesterase inhibitors in Lewy body dementia treatment trial (COBALT)
Dementia with Lewy bodies (DLB) and Parkinson’s disease dementia (PDD) are two neurodegenerative cause of dementia, in which patients are generally treated with Cholinesterase inhibitors. This is an NIHR Health Technology Assessment funded international multi-centre …
Using electronic patient records to examine patient outcomes in Dementia with Lewy bodies
Dementia with Lewy bodies (DLB) is the second most common neurodegenerative cause of dementia. However, people with DLB often experience missed or delayed diagnosis. The Clinical Record Interactive Search (CRIS) system allows research and service …
Deep tissue theranostic imaging
Funded by a recent Transformative Healthcare 2050 award from the EPSRC an interdisciplinary team of Southampton based scientists and researchers are developing new fibre lasers and novel methodologies that will allow early detection, imaging and …
Harnessing the heart-lung-brain interactions in the search for vascular biomarkers for neurological dysfunction
As an interdisciplinary team from University Hospital Southampton & University of Southampton comprising specialists in cardiothoracic surgery, ophthalmology, cardiac perfusion, imaging, mathematics and neuroanatomy we are in the optimal position to conduct a study in …
Adrenergic interventions for novel treatment strategies in Alzheimer’s disease
Computational modelling shows that innervation of vascular smooth muscle cells provides the motive force for IPAD, which has led us to hypothesize that 1) failure of elimination of Aβ along IPAD pathways could be a …
Understanding the dynamics and diversity of microglia in health and disease
Our lab is focused to studying the population of microglial cells from development to ageing, as well as chronic neurodegenerative disease such as Alzheimer’s. We have ongoing projects studying both rodent and human microglia, characterising …
Creating Learning Environments for Compassionate Care (CLECC) in mental health settings: an implementation study
We have developed and piloted a programme called Creating Learning Environments for Compassionate Care (CLECC), and this project pilots its use in mental health settings. In CLECC, all registered nurses and health care assistants from …