Dr Roxana Carare
Professor of Clinical Neuroanatomy and Experimental Neuropathology

 Theme Group:


Roxana Carare is a medically qualified Professor of Clinical Neuroanatomy and experimental neuropathology in the University of Southampton. Having graduated in general medicine in 1994 in Bucharest, Roxana completed her PhD in experimental neuropathology in 2006, in the University of Southampton, UK. The main international recognition for Roxana Carare has come from the neuroanatomy and neuropathology interdisciplinary research she leads, demonstrating the unique lymphatic drainage pathways by which fluid and soluble amyloid are eliminated from the brain along basement membranes within the walls of cerebral capillaries and arteries (Intramural Periarterial Drainage Pathways, IPAD).

 Current theme Projects:

Adrenergic interventions for novel treatment strategies in Alzheimer’s disease

Computational modelling shows that innervation of vascular smooth muscle cells provides the motive force for IPAD, which has led us to hypothesize that 1) failure of elimination of Aβ along IPAD pathways could be a …

Harnessing the heart-lung-brain interactions in the search for vascular biomarkers for neurological dysfunction

As an interdisciplinary team from University Hospital Southampton & University of Southampton comprising specialists in cardiothoracic surgery, ophthalmology, cardiac perfusion, imaging, mathematics and neuroanatomy we are in the optimal position to conduct a study in …

 Recent publications:


LD 66 Clinical Neurosciences
Southampton General Hospital
South Academic Block Level D MP806
SO16 6YD


Other iDeAC experts