Dr Jay Amin
Clinical Trials
Associate Professor in Psychiatry of Older Age

 Theme Group:


Dr Amin is an Associate Professor in Psychiatry of Older Age within Medicine at the University of Southampton. His research focus is on the role of inflammation in Dementia with Lewy bodies, Alzheimer’s disease and other neurodegenerative conditions. He is also principal investigator for several commercial and non-commercial trials at the Memory Assessment and Research Centre in Southampton.

 Current theme Projects:

Using electronic patient records to examine patient outcomes in Dementia with Lewy bodies

Dementia with Lewy bodies (DLB) is the second most common neurodegenerative cause of dementia. However, people with DLB often experience missed or delayed diagnosis. The Clinical Record Interactive Search (CRIS) system allows research and service …

Combining Memantine and Cholinesterase inhibitors in Lewy body dementia treatment trial (COBALT)

Dementia with Lewy bodies (DLB) and Parkinson’s disease dementia (PDD) are two neurodegenerative cause of dementia, in which patients are generally treated with Cholinesterase inhibitors. This is an NIHR Health Technology Assessment funded international multi-centre …

Diagnostic biomarkers of gut microbiome-associated phenotypes predictive of healthy aging and neurodegenerative disease (BIO-AGE)

The gastrointestinal tract in humans is one of the largest interfaces between the host and the environment. Different bacteria in the gut have been linked with longevity and healthy ageing. However, some of these bacteria …

Permeability of the blood-brain barrier in Alzheimer’s disease (PEBBAL) measured using dynamic contrast-enhanced MRI: a pilot study

Inflammation is the body’s normal response to injury and infection. It can be healthy or harmful depending on the situation. We know that when people with dementia get infections their memory symptoms can get worse. …

 Recent publications:


Memory Assessment and Research Centre
Tom Rudd Unit
Moorgreen Hospital
SO30 3JB

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