Dr Ian Galea
Translational diagnostics
Professor in Experimental Neurology

 Theme Group:


Dr Ian Galea is a clinician scientist who is internationally recognised for his work on the blood-brain barrier and haemoglobin neurotoxicity. His group work at the interface of laboratory and clinical medicine, with expertise in scientific measurement in health and disease. Of special interest to dementia researchers is a high-throughput urine test to measure systemic inflammation and a refined imaging method to measure blood-brain barrier permeability of the human brain. He is principal investigator of a study collecting cerebrospinal fluid, serum, urine and brain tissue samples, for use in neurodegenerative disease research.

 Current theme Projects:

Permeability of the blood-brain barrier in Alzheimer’s disease (PEBBAL) measured using dynamic contrast-enhanced MRI: a pilot study

Inflammation is the body’s normal response to injury and infection. It can be healthy or harmful depending on the situation. We know that when people with dementia get infections their memory symptoms can get worse. …

 Recent publications:


Clinical and Experimental Sciences
University of Southampton
South Lab & Path Block
Southampton General Hospital
SO16 6YD

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