The purpose for the executive group is to review iDeAC activity, promote and facilitate interdisciplinary working between themes and to support iDeAC strategic objectives including external collaborations and funding.

Professor Jessica Teeling 
Biological Sciences
Faculty of Environmental and Life Sciences
Life Sciences Building 85
University of Southampton
Highfield Campus
Southampton
SO17 1BJ

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Basic Science and Translation

Professor Jessica Teeling

Jessica Teeling is a professor in Experimental Neuroimmunology within Biological Sciences at the University of Southampton. Her research focuses on understanding the immune regulatory pathways in the healthy, diseased and ageing central nervous system (CNS). Her group studies the effect of antibody mediated inflammation in the CNS, and how these responses may contribute to the pathogenesis of neuroinflammatory and neurodegenerative diseases, such as Alzheimer’s disease, age related macular degeneration and systemic lupus erythematosis. She is particularly interested in the role of Fcgamma receptors and microglial activation.

 

Professor Sumeet Mahajan 
Institute of Life Sciences
University of Southampton
Highfield Campus
Southampton
SO17 1BJ

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Basic Science and Translation

Professor Sumeet Mahajan 

Sumeet Mahajan is a Professor in Molecular Biophotonics & Imaging in Chemistry with a joint appointment in the Institute for Life Sciences at the University of Southampton. His group works at the life science interface. The overarching aim of the research in his group is to develop new spectroscopy and imaging techniques and apply them to extract chemical information from biological systems to understand disease processes for early, faster or more sensitive healthcare diagnostics.

Dr Boyd Ghosh 
Salisbury NHS Foundation Trust
University Hospital Southampton NHS Foundation Trust

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Clinical Trials

Dr Boyd Ghosh

Dr Boyd Ghosh is a consultant neurologist. He graduated from St. Bartholomew’s and The Royal London Medical School in 2000. Junior medical posts were carried out in London, New Zealand and Bath. He was a Neurology clinical fellow in Frenchay (Bristol) before studying for a PhD in Cambridge with James Rowe and John Hodges. Research during his PhD involved Parkinson’s plus disorders with a particular emphasis on cognition and imaging in progressive supranuclear palsy (PSP). He is currently a consultant neurologist in the Wessex Neurological Centre in Southampton and Salisbury Hospital as well as honorary teacher at the University of Southampton.

Dr Jay Amin
Associate Professor in Psychiatry of Older Age

Memory Assessment and Research Centre
Tom Rudd Unit
Moorgreen Hospital
Southampton
SO30 3JB

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Clinical Trials

Dr Jay Amin

Dr Amin is an Associate Professor in Psychiatry of Older Age within Medicine at the University of Southampton. His research focus is on the role of inflammation in Dementia with Lewy bodies, Alzheimer’s disease and other neurodegenerative conditions. He is also principal investigator for several commercial and non-commercial trials at the Memory Assessment and Research Centre in Southampton.

His research focus is on the role of inflammation in Dementia with Lewy bodies, Alzheimer’s disease and other neurodegenerative conditions. He is also principal investigator for several commercial and non-commercial trials at the Memory Assessment and Research Centre in Southampton.

Professor Jackie Bridges
Health Sciences Student Office
University of Southampton
Highfield Southampton
SO17 1BJ

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Dementia Care and Prevention

Professor Jackie Bridges

Jackie Bridges is a professor of Older’s People Care at the University of Southampton. Her programme of work focuses on the organisation and delivery of health care to older people with complex needs. She leads a major programme of research focused on professional work and organisational change related to older people’s care, and steers the development and delivery of associated educational provision within Health Sciences. Jackie leads the Ageing and Dementia research theme and is an investigator for NIHR CLAHRC Wessex. She is also Director for the NIHR CLAHRC Wessex Research Capacity in Dementia Care programme

Dr Angela Darekar
Department of Medical Physics
University Hospital Southampton NHS Foundation Trust

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Imaging (human)

Dr Angela Darekar

Angela is the Lead for MRI Physics at University Hospital Southampton, and has many years of experience of using, developing and enabling clinical MRI techniques, in both clinical and research settings. Her role includes supporting both the clinical MRI service (e.g. service development, QA and MRI safety), and supporting research projects utilising MRI, from both within UHS and the University of Southampton, thus covering a wide range of applications. She has a keen interest in facilitating and encouraging the translation of research MRI techniques into the clinical setting, working closely with clinical colleagues and using her expertise in MRI physics to successfully enable this. She is also heavily involved in co-ordinating the MRI research programme for the Trust and University.

Dr Tony Birch

Head of Neurological Physics
Department of Medical Physics and Bioengineering
University Hospital Southampton NHS Foundation Trust

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Imaging (human)

Dr Tony Birch

Dr Tony Birch is a clinical scientist specialising in measurement of fluid flow in the brain. His particular expertise is the application of transcranial Doppler ultrasound to measure the velocity of blood flowing in the major arteries at the base of the brain. As well as performing these measurements as a clinical service, he provides a transcranial Doppler training course for health professionals from across the UK.

Tony is very active in research where he has two primary goals; in collaboration with others he is developing:

  1. New methods to measure how well the brain can regulate its own blood supply (cerebral autoregulation).
  2. New methods to measure the fluid pressure on the brain (cerebrospinal fluid pressure).

Both of these measurements are desperately needed to improve the care of patients with conditions including stroke, dementia, head trauma, meningitis, hydrocephalus, sickle cell disease and many more, less well known, and often mis-diagnosed conditions.

Dr Anton Page
Biomedical Imaging Unit
Laboratory and Pathology Block
Southampton General Hospital
Southampton
SO16 6YD.

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Imaging (tissue)

Dr Anton Page

Dr Anton Page is the Head of The Biomedical Imaging Unit, a joint University Hospitals Southampton NHS Foundation Trust (UHS)/University of Southampton (UoS) facility for high quality/high resolution diagnostic and research microscopy. Accredited under UKAS to ISO 15189, this core facility carries out research work for UoS, other universities and research institutes, industry and artists, together with diagnostic microscopy for UHS, and other hospitals both nationally and internationally.

Associate Professor Diego Gomez-Nicola
Biological Sciences University of Southampton
South Lab & Path Block
Southampton General Hospital
Southampton
SO16 6YD

Website:

www.dgnlab.co.uk

External collaborations and industry

Associate Professor Diego Gomez-Nicola

Dr Diego Gomez-Nicola is Associate Professor within Biological Sciences at the University of Southampton. As a neuroscientist, Dr Gomez-Nicola is interested in unveiling the roles of glial cells in the healthy and diseased brain, as a way to understand the fascinating complexity of our brain.

The goal of his current research is to study the regulation of microglial proliferation during chronic neurodegenerative diseases such as prion or Alzheimer’s. The expansion of the microglial population is a hallmark of neurodegeneration and contributes to the development of the pathology. A detailed understanding of the molecules and mechanisms orchestrating microglial proliferation could open a window to elaborate therapeutic approaches to control the neuroinflammatory component of the disease.