Clinical academic training in dementia research
The future of dementia research depends on developing the future research workforce in dementia. iDeAC is committed to train aspiring young clinical academic trainees aspiring to pursue a research career in dementia, whether this is clinical or laboratory oriented. If you are such an individual looking to apply for an Academic Foundation Programme post, Academic Clinical Fellow or Clinical Lecturer in dementia-related research, we can help you. There are a broad array of researchers you can work with, covering interests ranging from preclinical studies and neuropathology to clinical studies, drug trials and applied health research in dementia care. Many are listed on this website, and you can contact investigators directly. If you are interested in a specific area of dementia research, you can make an enquiry with us by emailing firstname.lastname@example.org and we will put you in touch with the investigator most closely allied with your interest.
Southampton Clinical Academic Training Scheme
The well-established Southampton Clinical Academic Training Scheme (SoCATS) runs induction programmes and looks after the general needs of clinical academic trainees. A research training course tailored for the younger Academic Foundation Programme trainees is held annually. Specific workshops are held to help trainees at Academic Clinical Fellow or Clinical Lecturer levels to develop their own ideas, write fellowship grants, and communicate science, and prepare them for fellowship interviews. Trainees will be invited to identify one or more mentors from the Faculty’s Mentoring Database.
Title: Blood-brain barrier integrity in dementia
Supervisors: Dr Jay Amin & Dr Ian Galea
Overview: Several studies suggest that blood-brain barrier integrity is impaired in Alzheimer’s dementia. In this project it is hypothesized that dynamic contrast enhanced magnetic resonance imaging can be used to demonstrate this phenomenon, comparing Alzheimer’s dementia, Lewy body dementia and control individuals. The relationship of blood-brain barrier permeability to systemic inflammatory status as measured by urinary neopterin-to-creatinine ratio and blood cytokine assays is being investigated. Patients are being followed up to determine whether a baseline MRI assessment of blood-brain barrier integrity is predictive of future cognitive decline. The Academic Clinical Fellow working on the project may come from Psychiatry or Neurology backgrounds.